I’ll echo what some others said about Portal, but here’s a handful of games that I’ve enjoyed for their comedic value:

What the Golf is pretty funny if you like/hate mini golf.

Many of the LEGO games have some good humor: Star Wars is my favorite, but LEGO City Undercover was fantastic, too.

Borderlands 2 has some great comedy, with The Pre-Sequel as a decent runner up.

The Yakuza games are fantastic; I recommend Yakuza Kiwami for a low-cost entry that allows you to dip your toes in and get the feel for it

Untitled Goose Game is funny because you make it funny.