Since Nexus Mod Manager for Linux fizzled out, I was excited to find a decent mod manager. It has built-in support for about 100 games, but adding other games seems pretty easy. I pasted in the Steam ID and path the the .exe of a proton game (MineMogul), and then everything just worked.
There’s also an install script for pure MO2. Will edit soon to include links
EDIT: Sauce, as promised. Also I followed this guide to walk through the process.
Also, there’s another installer that’s been archived and replaced with Fluorine, a full Linux port of MO2, but it uses LLM’s (like Amethyst does)
Hope this helps